We are currently seeking applications for two post-doctoral positions relating to the functional and comparative genome analysis of lactic acid bacteria and bifidobacteria.
The existing research team comprises a large, dynamic and high-achieving group of post-doctoral researchers, PhD students and research assistants, and is embedded within the School of Microbiology and APC Microbiome Ireland with associated state-of-the-art equipment and infrastructure. Details of the two available positions are presented below.

1. Post-doctoral researcher (2-year contract) Bifidobacterial genomics and bioinformatics
The ideal candidate for this post, which will be specifically associated with the BioIT platform of APC Microbiome Ireland, will have a under- and/or postgraduate degree in bioinformatics and/or possess a PhD degree with extensive bioinformatics skills pertaining to ‘omics’ data, such as comparative genomics, metagenomics, transcriptomics and/or metabolomics, ideally in the context of gut microbiota or other complex microbial consortia. Relevant bioinformatics experience, and associated expertise and skills should be supported by a corresponding publication track record in peer-reviewed scientific journals and/or be demonstrated through other means of knowledge transfer.
Applications for this position (Job ID: 044911) can be made through the following link: https://my.corehr.com/pls/uccrecruit/erq_search_package.search_form?p_company=5023&p _internal_external=E

2. Post-doctoral researcher (18 month contract) BacTrans: Natural DNA transfer systems for bacterial starter cultures
BacTrans is an industry-partnered project that aims to identify and exploit natural DNA transfer systems including, but not limited to, conjugation and phage-mediated transduction. The objective of this study is to develop novel and technologically robust strains of Lactococcus lactis and Streptococcus thermophilus, particularly with respect to phage-resistance, for commercial use as so-called starter cultures in the dairy and fermented (functional) food industries.
The project will involve identification and molecular characterisation of phageresistance and DNA transfer systems. Applicants should ideally possess a MSc and PhD degree in biochemistry, genetics, biotechnology, (molecular) microbiology or related discipline, and have a corresponding publication track-record.
The post-doctoral researcher is expected to be directly involved in the research activities of the BacTrans project including execution of individual project goals and guidance of PhD students to ensure the timely execution of the project goals, while also contributing the communication of the research findings emanating from the research.
Experience, expertise and skills should ideally be supported by a corresponding publication track record or other means of knowledge transfer. Applications for this position (Job ID: 044371) can be made through the following link: https://my.corehr.com/pls/uccrecruit/erq_search_package.search_form?p_company=5023&p _internal_external=E

For informal information please contact: Prof Douwe van Sinderen (d.vansinderen@ucc.ie) or Dr Jennifer Mahony (j.mahony@ucc.ie).

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We have an opening for a Postdoctoral Fellow to help out with an NIH funded project aimed at the molecular characterization of a bacterial natural product involved in host immune interaction. You will join the Claesen group at the Cleveland Clinic Lerner Research Institute and Center for Microbiome and Human Health. Visit our lab website to meet us: https://claesengroup.org/

Our group’s aim is to functionally characterize molecular mechanisms that control bacterial interspecies and microbe-host interactions in the human microbiome. Bacteria use small molecule chemicals to mediate these interactions and the genetic information required for their production is typically encoded in one physical location of the bacterial chromosome, in biosynthetic gene clusters (BGCs). Using in silico techniques, we identified several widespread families of BGCs that we are now characterizing experimentally, prioritizing on the BGCs predicted to be involved in modulation of community composition or interaction with the host immune system. Our research will contribute to a better mechanistic understanding of the microbes that live in our body, leading to the discovery of druggable small molecules, new targets for antibacterial therapy and beneficial bacterial strains that can be employed for intervention therapies.

Your profile
You will have (or are close to obtaining) a PhD degree in a relevant (bio)chemical or biological subject and a good publication record in peer-reviewed scientific journals. You’re a motivated and creative scientist with hands-on experience in analytical chemistry, (bio)synthesis, biochemical assays and standard microbiological techniques. You’re interested in learning more about microbial genetics, mouse infection/colonization models or microbiome science.

About us
The areas of expertise in the Claesen group include microbiology, bacterial genetics and synthetic biology, small molecule biosynthesis and biochemistry, and animal models for microbiome studies of metabolic disease and cancer development. We provide a stimulating, multidisciplinary training environment that will assist you in your successful scientific development. You will receive a competitive salary and benefits package, and have access to state-of-the-art core facilities in the Lerner Research Institute (http://www.lerner.ccf.org/), as well as plenty of opportunities for clinical collaboration at the Cleveland Clinic, the #2 Hospital in the Nation. Cleveland living is affordable and family friendly, offering a range in activities that include an amazing nature parks, museums, major professional sports teams, an extensive theater district and blooming microbrewery scene.

How to apply
Contact Dr. Jan Claesen (claesej@ccf.org) for more info. To apply, please email your CV, a brief summary of research interests (no more than 2 pages) and contact information for 3 references.

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We are looking for a highly motivated and self-driven postdoctoral researcher to add to our Molecular Microbiology Unit at the Department of Biology and Biotechnology “Lazzaro Spallanzani” at the University of Pavia (Italy). The position corresponds to a 1 year-fellowship (“Assegno di ricerca di tipo B”), possibly renewable for 4 years and available from May-June 2021.

Our Unit has a recognized experience in the study of the mechanism of action and of resistance of new antitubercular drugs. Tuberculosis remains the leading cause of mortality due to a bacterial pathogen, Mycobacterium tuberculosis. Moreover, M. tuberculosis drug-resistant strains are becoming a threat to public health worldwide.

We are looking to hire a postdoctoral fellow to lead the isolation and screening of bacterial isolates and design of protective collaboromes. The postdoc will primarily use a combination of classical microbial isolation techniques and high throughput screening assays. The postdoc position is for 2.5 years and will be carried out at Section of Microbiology, Department of Biology, University of Copenhagen. The Fellow will engage in an international teamwork in a new interdisciplinary project funded by the Bio-Innovation Institute.

The position is available from June 1st 2021.

Further information on the Department is linked at http://www.science.ku.dk/english/about-the-faculty/organisation/. Inquiries about the position can be made to Prof. Søren J. Sørensen, PhD (sjs@bio.ku.dk).

Postdoctoral fellowship in Design of bacterial collaboromes for biocontrol of potato pathogens (ku.dk)

We are looking for a highly qualified research assistant for a 2.5-year full time position on the project: “The design of bacterial collaboromes for biocontrol of potato pathogens”. The qualified applicant will be working in close collaboration with the postdoctoral fellow in lead, and will be involved in both research- and wet-lab related assignments.

The position is available from June 1st 2021, or as soon as possible here after, at the Department of Biology at the University of Copenhagen, Denmark.

Further information on the Department is linked at http://www.science.ku.dk/english/about-the-faculty/organisation/. Inquiries about the position can be made to Prof. Søren J. Sørensen, PhD (sjs@bio.ku.dk).

Full time Research Assistant to assist on the project "Design of bacterial collaboromes for biocontrol of potato pathogens" (ku.dk)

In the context of the project “Molecular characterization of disease-linked polynucleotide phosphorylase (hPNPase) variants (POLYVAR)” funded by Fondazione Telethon, we are seeking:

1. a highly motivated Ph.D. graduate for a 24-month research post-doctoral fellowship (extensible for further 6 months)

2. a Master’s degree graduate for a junior research fellowship (Borsa di studio)

The project aims at the molecular characterization of human PNPase (hPNPase) variants causing different neurological diseases by exploiting Escherichia coli and human cell lines as models. The effect of the mutations on transcription profile and PNPase-dependent phenotypes will be characterized in both systems, with the final aim to correlate specific molecular defects of hPNPase variants with the severity degree of the disease observed in the patients.

For the post-doctoral position, expertise in molecular biology techniques such as RT-qPCR and cloning strategies is required. Familiarity with biochemistry and RNA characterization will be positively evaluated. For the junior research fellowship, a Master’s thesis with honours in Biology/Biotechnology is required. Excellent oral and writing English skills are required for both candidates.

Candidates interested in applying can send a CV/resume and a short presentation letter (with one contact of a previous mentor for junior fellowship candidates and two contacts for Post-Doc candidates) to Prof. Federica Briani (federica.briani@unimi.it) no later than April 15, 2021.

For more details, please contact Prof. Federica Briani.